Custer, Laura M.: search on Z-Library

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1

Establishing best practise in the application of expert review of mutagenicity under ICH M7

Barber, Chris, Amberg, Alexander, Custer, Laura, Dobo, Krista L., Glowienke, Susanne, Van Gompel, Jacky, Gutsell, Steve, Harvey, Jim, Honma, Masamitsu, Kenyon, Michelle O., Kruhlak, Naomi, Muster, Wol

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.36 MB

english, 2015

2

Principles and procedures for handling out-of-domain and indeterminate results as part of ICH M7 recommended (Q)SAR analyses

Amberg, Alexander, Andaya, Roxanne V., Anger, Lennart T., Barber, Chris, Beilke, Lisa, Bercu, Joel, Bower, Dave, Brigo, Alessandro, Cammerer, Zoryanna, Cross, Kevin P., Custer, Laura, Dobo, Krista, Ge

Journal:

Regulatory Toxicology and Pharmacology

Year:

2018

Language:

english

File:

PDF, 746 KB

english, 2018

3

Nonclinical safety assessment of epigenetic modulatory drugs: Current status and industry perspective

Reynolds, Vincent L., Butler, Paul, Abernathy, Matthew M., Aschenbrenner, Laura, Best, Derek D., Blank, Jim, Crosby, Meredith, Custer, Laura, Escobar, Patricia A., Kolaja, Kyle, Moggs, Jonathan, Shuey

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

File:

PDF, 487 KB

2020

4

International Pig-a gene mutation assay trial (Stage III): Results with N-methyl-N-nitrosourea

Anthony M. Lynch, Amanda Giddings, Laura Custer, Carol Gleason, Andrew Henwood, Mike Aylott, Julia Kenny

Journal:

Environmental and Molecular Mutagenesis

Year:

2011

Language:

english

File:

PDF, 1.44 MB

english, 2011

5

Follow-up actions from positive results of in vitro genetic toxicity testing

Kerry L. Dearfield, Véronique Thybaud, Michael C. Cimino, Laura Custer, Andreas Czich, James S. Harvey, Susan Hester, James H. Kim, David Kirkland, Dan D. Levy, Elisabeth Lorge, Martha M. Moore, Glady

Journal:

Environmental and Molecular Mutagenesis

Year:

2011

Language:

english

File:

PDF, 405 KB

english, 2011

6

International Pig-a gene mutation assay trial: Evaluation of transferability across 14 laboratories

Stephen D. Dertinger, Souk Phonethepswath, Pamela Weller, John Nicolette, Joel Murray, Paul Sonders, Hans-Werner Vohr, Jing Shi, Ljubica Krsmanovic, Carol Gleason, Laura Custer, Andrew Henwood, Kevin

Journal:

Environmental and Molecular Mutagenesis

Year:

2011

Language:

english

File:

PDF, 1.14 MB

english, 2011

7

Principles and procedures for implementation of ICH M7 recommended (Q)SAR analyses

Amberg, Alexander, Beilke, Lisa, Bercu, Joel, Bower, Dave, Brigo, Alessandro, Cross, Kevin P., Custer, Laura, Dobo, Krista, Dowdy, Eric, Ford, Kevin A., Glowienke, Susanne, Van Gompel, Jacky, Harvey,

Journal:

Regulatory Toxicology and Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.12 MB

english, 2016

8

Cartilage damage caused by metal implants applied for the treatment of established localized cartilage defects in a rabbit model

Roel J.H. Custers, Laura B. Creemers, Mattie H.P. van Rijen, Ab J. Verbout, Daniel B.F. Saris, Wouter J.A. Dhert

Journal:

Journal of Orthopaedic Research

Year:

2009

Language:

english

File:

PDF, 301 KB

english, 2009

9

Probabilistic Neural Network Multiple Classifier System for Predicting the Genotoxicity of Quinolone and Quinoline Derivatives

He, Linnan, Jurs, Peter C., Kreatsoulas, Constantine, Custer, Laura L., Durham, Stephen K., Pearl, Greg M.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 204 KB

english, 2005

10

Extending (Q)SARs to incorporate proprietary knowledge for regulatory purposes: A case study using aromatic amine mutagenicity

Ahlberg, Ernst, Amberg, Alexander, Beilke, Lisa D., Bower, David, Cross, Kevin P., Custer, Laura, Ford, Kevin A., Van Gompel, Jacky, Harvey, James, Honma, Masamitsu, Jolly, Robert, Joossens, Elisabeth

Journal:

Regulatory Toxicology and Pharmacology

Year:

2016

Language:

english

File:

PDF, 2.91 MB

english, 2016

11

The novel actin nucleator Cordon-bleu interacts with Syndapins during epithelial development

Laura Custer, Elizabeth Driver, Kent Wood, John Klingensmith

Journal:

Developmental Biology

Year:

2009

Language:

english

File:

PDF, 55 KB

english, 2009

12

16-P014 Cordon-bleu is a developmentally regulated, novel actin nucleator that plays a role in epithelial ciliogenesis

John Klingensmith, Laura Custer, Elizabeth Driver, Andrew Ravanelli

Journal:

Mechanisms of Development

Year:

2009

Language:

english

File:

PDF, 38 KB

english, 2009

13

In vivo flow cytometric Pig-a and micronucleus assays: Highly sensitive discrimination of the carcinogen/noncarcinogen pair benzo(a)pyrene and pyrene using acute and repeated-dose designs

Dorothea K. Torous, Souk Phonethepswath, Svetlana L. Avlasevich, Jared Mereness, Steven M. Bryce, Jeffrey C. Bemis, Pamela Weller, Sara Bell, Carol Gleason, Laura L. Custer, James T. MacGregor, Stephe

Journal:

Environmental and Molecular Mutagenesis

Year:

2012

Language:

english

File:

PDF, 519 KB

english, 2012

14

Replacement of the medial tibial plateau by a metallic implant in a goat model

Roel J.H. Custers, Daniel B.F. Saris, Laura B. Creemers, Ab J. Verbout, Mattie H.P. van Rijen, Simon C. Mastbergen, Floris P. Lafeber, Wouter J.A. Dhert

Journal:

Journal of Orthopaedic Research

Year:

2010

Language:

english

File:

PDF, 325 KB

english, 2010

15

Adenovirus Serotype 5 Hexon Mediates Liver Gene Transfer

Simon N. Waddington, John H. McVey, David Bhella, Alan L. Parker, Kristeen Barker, Hideko Atoda, Rebecca Pink, Suzanne M.K. Buckley, Jenny A. Greig, Laura Denby, Jerome Custers, Takashi Morita, Ivo M.

Journal:

Year:

2008

Language:

english

File:

PDF, 1.77 MB

english, 2008

16

Finding a Balance: How Diverse Dosage Compensation Strategies Modify Histone H4 to Regulate Transcription

Wells, Michael B., Csankovszki, Györgyi, Custer, Laura M.

Journal:

Genetics Research International

Year:

2012

Language:

english

File:

PDF, 3.21 MB

english, 2012

17

Cordon-Bleu Is an Actin Nucleation Factor and Controls Neuronal Morphology

Rashmi Ahuja, Roser Pinyol, Nicole Reichenbach, Laura Custer, John Klingensmith, Michael M. Kessels, Britta Qualmann

Journal:

Year:

2007

Language:

english

File:

PDF, 2.10 MB

english, 2007

18

Stereospecific Differences in Repair by Human Cell Extracts of Synthesized Oligonucleotides Containing trans-Opened 7,8,9,10-Tetrahydrobenzo[ a ]pyrene 7,8-Diol 9,10-Epoxide N 2 -dG Adduct Stereoisomers Located within the Human K- ras Codon 12 Sequence †

Custer, Laura, Zajc, Barbara, Sayer, Jane M., Cullinane, Carleen, Phillips, Don R., Cheh, Albert M., Jerina, Donald M., Bohr, Vilhelm A., Mazur, Sharlyn J.

Journal:

Year:

1999

Language:

english

File:

PDF, 185 KB

english, 1999

19

Opportunities to integrate new approaches in genetic toxicology: An ILSI-HESI workshop report

Zeiger, Errol, Gollapudi, Bhaskar, Aardema, Marilyn J., Auerbach, Scott, Boverhof, Darrell, Custer, Laura, Dedon, Peter, Honma, Masamitsu, Ishida, Seiichi, Kasinski, Andrea L., Kim, James H., Manjanat

Journal:

Environmental and Molecular Mutagenesis

Year:

2015

Language:

english

File:

PDF, 104 KB

english, 2015

20

Genetic Toxicology Testing || The In Vivo Rodent Micronucleus Assay

Year:

2016

Language:

english

File:

PDF, 2.36 MB

english, 2016

21

Predicting the Genotoxicity of Secondary and Aromatic Amines Using Data Subsetting to Generate a Model Ensemble.

Brian E. Mattioni, Gregory W. Kauffman, Peter C. Jurs, Laura L. Custer, Stephen K. Durham, Greg M. Pearl

Journal:

Year:

2003

File:

PDF, 55 KB

2003

22

Collaborative study on fifteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies

Andreas Rothfuss, Mike O’Donovan, Marlies De Boeck, Dominique Brault, Andreas Czich, Laura Custer, Shuichi Hamada, Ulla Plappert-Helbig, Makoto Hayashi, Jonathan Howe, Andrew R. Kraynak, Bas-jan van d

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2010

Language:

english

File:

PDF, 800 KB

english, 2010

23

Use of in silico systems and expert knowledge for structure-based assessment of potentially mutagenic impurities

Sutter, Andreas, Amberg, Alexander, Boyer, Scott, Brigo, Alessandro, Contrera, Joseph F., Custer, Laura L., Dobo, Krista L., Gervais, Veronique, Glowienke, Susanne, Gompel, Jacky van, Greene, Nigel, M

Journal:

Regulatory Toxicology and Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.26 MB

english, 2013

24

Using Expert Driven Machine Learning to Enhance Dynamic Metabolomics Data Analysis

Beirnaert, Charlie, Peeters, Laura, Meysman, Pieter, Bittremieux, Wout, Foubert, Kenn, Custers, Deborah, Van der Auwera, Anastasia, Cuykx, Matthias, Pieters, Luc, Covaci, Adrian, Laukens, Kris

Journal:

Year:

2019

Language:

english

File:

PDF, 2.68 MB

english, 2019

25

Extending (Q)SARs to incorporate proprietary knowledge for regulatory purposes: is aromatic N-oxide a structural alert for predicting DNA-reactive mutagenicity?*

Amberg, Alexander, Anger, Lennart T, Bercu, Joel, Bower, David, Cross, Kevin P, Custer, Laura, Harvey, James S, Hasselgren, Catrin, Honma, Masamitsu, Johnson, Candice, Jolly, Robert, Kenyon, Michelle

Journal:

Year:

2018

Language:

english

File:

PDF, 907 KB

english, 2018

26

Predicting the Genotoxicity of Thiophene Derivatives from Molecular Structure

Mosier, Philip D., Jurs, Peter C., Custer, Laura L., Durham, Stephen K., Pearl, Greg M.

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 181 KB

english, 2003

27

Predicting the Genotoxicity of Polycyclic Aromatic Compounds from Molecular Structure with Different Classifiers

He, Linnan, Jurs, Peter C., Custer, Laura L., Durham, Stephen K., Pearl, Greg M.

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 111 KB

english, 2003

28

The onset of C. elegans dosage compensation is linked to the loss of developmental plasticity

Custer, Laura M., Snyder, Martha J., Flegel, Kerry, Csankovszki, Györgyi

Journal:

Developmental Biology

Year:

2014

Language:

english

File:

PDF, 10.84 MB

english, 2014

29

Exposure and effects of perfluoroalkyl compounds on tree swallows nesting at Lake Johanna in east central Minnesota, USA

Christine M. Custer, Thomas W. Custer, Heiko L. Schoenfuss, Beth H. Poganski, Laura Solem

Journal:

Reproductive Toxicology

Year:

2012

Language:

english

File:

PDF, 332 KB

english, 2012

30

Bone morphogenetic protein 4 mediates myocardial ischemic injury through JNK-dependent signaling pathway

Alok S. Pachori, Laura Custer, Don Hansen, Shannon Clapp, Erica Kemppa, John Klingensmith

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2010

Language:

english

File:

PDF, 1.91 MB

english, 2010

31

Development of a real-time physicianâpatient communication data collection tool

Custer, Adam, Rein, Laura, Nguyen, Daniel, Wentworth, Karen, Dhamoon, Amit

Journal:

BMJ Open Quality

Year:

2019

File:

PDF, 172 KB

2019

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